Review Article

The Role of Salt in the Pathogenesis of Fructose-Induced Hypertension

Figure 1

Localization of Glut2 and Glut5 in jejunum and their regulation in response to increased dietary fructose intake. Glut5 which only transports fructose but not glucose resides in the apical membrane at basal state (a) and is activated in response to increased dietary fructose intake (b). Glut2 which can transport both glucose and fructose is expressed in the cytoplasm and on basolateral membrane at basal state (a) and is recruited to the apical membrane in the presence of increased dietary fructose or glucose intake.
392708.fig.001a
(a)
392708.fig.001b
(b)