Comparison of Sustained Hemodiafiltration with Acetate-Free Dialysate and Continuous Venovenous Hemodiafiltration for the Treatment of Critically Ill Patients with Acute Kidney Injury
Table 3
Baseline characteristics of patients.
Characteristic
CVVHDF
SHDF
P value
No. of patients (male/female)
25 (17/8)
25 (16/9)
NS
Age (years)
65.3 ± 13.1
66.5 ± 12.1
NS
Cause of acute kidney injury (%)
NS
Nephrogenic
20
24
Sepsis
52
48
Cardiogenic
12
12
Postsurgical
8
8
Drug induced
0
4
Hepatic failure
4
4
Other
4
0
Presence of CKD on admission (%)
40
44
NS
APACHE II score
19.6 ± 3.7
20.0 ± 4.3
NS
SOFA score
8.1 ± 2.0
8.2 ± 3.2
NS
RIFLE classification
R (%)
20
20
NS
I (%)
44
40
NS
F (%)
36
40
NS
Mechanically ventilated (%)
36
32
NS
Oliguric (%)
60
60
NS
Baseline systolic blood pressure (mmHg)
107 ± 32
110 ± 29
NS
Required vasopressors (%)
28
24
NS
Renal parameters at RRT initiation
Serum urea nitrogen (mg/dL)
69 ± 26
68 ± 24
NS
Serum creatinine (mg/dL)
4.6 ± 2.3
4.8 ± 2.1
NS
Days from ICU admission to RRT
2.1 ± 1.3
2.1 ± 1.5
NS
APACHE: acute physiology and chronic health evaluation; CKD: chronic kidney disease; CVVHDF: continuous venovenous hemodiafiltration; ICU: intensive care unit; RIFLE: Risk, Injury, and Failure with the outcome classes Loss and End-stage kidney disease classification system; RRT: renal replacement therapy; SOFA: sequential organ failure assessment; SHDF: sustained hemodiafiltration.
