Recurrent Focal Segmental Glomerulosclerosis: A Discrete Clinical Entity

Figure 1

Immediate recurrence of FSGS (rFSGS) following deceased donor kidney transplantation. A 15-year-old girl with steroid-resistant FSGS had bilateral nephrectomy prior to transplantation. Proteinuria recurred within the first 12 hours but was controlled with intensive plasma exchange therapy (1.5 plasma volumes with albumin replacement). Efforts to wean plasmapheresis lead to a rise in urine protein/creatinine ratio (g/g) on several occasions. Each triangle represents a plasma exchange.