Serum Galactose-Deficient IgA1 Level Is Not Associated with Proteinuria in Children with IgA Nephropathy

Table 1

Clinical and demographic features of individual subjects (incident cases).

Subject	Race/gender	Presentation	Age at	estGFR	Urinary protein/	BMI	SBP/DBP	Serum Gd-IgA1
			biopsy	(mL/min/1.73 m^2)	creatinine ratio	percentile	percentile	level (units/mL)
A1	C/M	Microhematuria,	17.6	59	1.17	98	95–99/<50	262
		proteinuria
M2	C/M	Isolated proteinuria	13.8	78	1.24	26	95–99/50–90	889
M15	C/F	Gross hematuria	11.2	80	1.31	<1	<50/50–90	1076
M16	C/F	Gross hematuria	8.7	75	1.00	57	50–90/<50	1073
M17	C/M	Gross hematuria	13.4	108	3.10	11	50–90/50–90	1534
M18	C/F	Recurrent gross hematuria	12.5	107	2.96	17	>99/<50	1155
M19	AA/F	Gross hematuria,	15.9	49	2.97	52	<50, <50	3401
		rapidly progressive
		glomerulonephritis
M21	AA/M	Isolated proteinuria	5.1	94	3.58	96	<50, 50–90	747
M22	C/M	Gross hematuria,	8.6	75	1.33	49	95–99/50–90	803
		acute kidney injury
M26	AA/M	Gross hematuria	8.8	120	3.70	30	90–95/50–90	470
M28	C/F	Gross hematuria,	16.7	63	1.36	40	90–95/50–90	1110
		proteinuria
M29	C/M	Gross hematuria	12.8	96	0.95	41	>99/95–99	659
M30	C/M	Gross hematuria,	15.0	61	2.89	63	90–95/50–90	364
		acute kidney injury
M31	C/M	Gross hematuria	16.2	84	0.25	89	50–90/50–90	2513
T2	C/M	Microhematuria, proteinuria,	17.8	40	1.27	44	95–99/50–90	796
		Chronic kidney
		disease stage 3

AA: African-American; BMI: body mass index; C: Caucasian; estGFR, estimated glomerular filtration rate; DBP: diastolic blood pressure; SBP: systolic blood pressure; microhematuria, >5 RBC/high powered field.