Effect of Sertraline on Uremic Pruritus Improvement in ESRD Patients

Table 2

The mean ± SD of laboratory tests before and after treatment with sertraline.

Parameter	Before treatment	After treatment	Normal range
Calcium	8.1 ± 1.3 (mg/dL)	8.2 ± 1.5 (mg /dL)	8.2–10.2 mg/dL
Phosphorus	6.8 ± 1.1 (mg/dL)	6.7 ± 1.4 (mg/dL)	3.3–5.5 mg/dL
Alkaline phosphatase	392.6 ± 205.6 (IU/L)	415.7 ± 224.2 (IU/L)	20–120 IU/L
Albumin	4.08 ± 1.4 (g/dL)	3.8 ± 0.6 (g/dL)	3.2–4.8 g/dL
Parathyroid hormone	314.3 ± 199.8 (pg/mL)	301.7 ± 210.5 (pg/mL)	50–330 pg/mL
Hematocrit	31.06 ± 2.9 (%)	32.5 ± 3.4 (%)	M: 42–52%; F: 35–47%
BUN	56 ± 12.3	31 ± 4.3	10–20 mg/dL
Cr	7.2 ± 1.2	4.1 ± 1.1	0.7–1.4 mg/dL
URR^1		64%	>65%
Kt/V^2		1.1	>1.2

¹URR: urea reduction ratio: this percent stands for 4-month-period.
²Kt/V: Kt stands for dialyzer clearance multiplied by time (mL/min) and V for volume of water a patient's body contains.