Table 1: Patients’ characteristics and clinical course in subjects with end-stage renal failure presenting with calciphylaxis.

Subject Patient 1 Patient 2 Patient 3 Patient 4 Patient 5 Patient 6 Age (years) 48 53 63 72 74 86 Gender Female Female Female Female Male Male Cause of ESRF Diabetes Chronic GN Diabetes Diabetes Diabetes Obstructive uropathy Duration RRT (months) 12 36 24 21 15 12 Site of lesion Extensive* Distal Distal Extensive Distal Distal Microorganism Pseudomonas MRSA Klebsiella Pseudomonas Pseudomonas MRSseudomonas Mode of therapy** Cinacalcet STS PTHX HBO PTHX HBO STS prednisolone Cinacalcet prednisolone STS HBO amputation Cinacalcet HBO Outcome Dead Dead Dead Dead Dead Alive Cause of death Sepsis Myocardial infarction Sepsis Myocardial infarction Sepsis Not applicable Comorbidities DM ESRF IHD HTN Asthma Epilepsy ESRF gout DM ESRF gout IHD DM ESRF MGUS DM ESRF HTN arthritis ESRF Skin lesion outcome Failed Healed Failed Healed Failed Healed Survival (months) 1 32 5 4 4 Alive

ESRF: end-stage renal failure, GN: glomerulonephritis, RRT: renal replacement therapy, *: extensive skin lesions involving the lower limbs, genitalia, abdominal wall, and breast, MRSA: methicillin resistant Staph aureus, **: mode of therapy apart from general wound care and antibiotics, STS: sodium thiosulphate, PTHX: parathyroidectomy, HBO: hyperbaric oxygen, IHD: ischemic heart disease, HTN: hypertension, MGUS: monoclonal gammopathy of unknown significance.