Review Article

Mechanisms of Glomerular Albumin Filtration and Tubular Reabsorption

Table 2

Glomerular filtration and reabsorption of albumin and low-molecular weight proteins (LMWP) in humans estimated from rat micropuncture data [12].

AlbuminLMWP

Bowman’s capsule concentration22.9 μg/mL72.1 μg/mL
Plasma concentration37.0 mg/mL73.0 μg/mL
Sieving coefficient0.000620.987
Estimated glomerular filtration amount in humans22.9 μg/mL × 100 mL/min × 24 h × 60 min = 3.3 g/day72.1 μg/mL × 100 mL/min × 24 h × 60 min = 10.4 g/day
Estimated tubular reabsorption in humans3.2 g/day9.6 g/day