Ref Risk factor Statistics Result Meth. quality Ethnicity [13 ] Aboriginal ethnicity (versus non-indigenous ethnicity) IRR (adj.) 1.93 (1.63–2.28) Good [39 ] Aboriginal ethnicity (versus white) HR (adj.) 1.78 (1.45–2.19) Average [15 ] Indigenous and remote living (versus other) HR (adj.) 1.92 (1.69–2.18) Good [16 ] First Nations people (versus other) Comp. of PET (not adj.)
Good [28 ] Black ethnicity (versus other) IRR (adj.) 2.2 (
) Average [14 ] Black ethnicity (versus white) HR (adj.) 1.255 (1.178–1.338) Good [37 ] Black ethnicity (versus white) HR (adj.) 1.5 (1.2–1.8) Average [30 ] Black ethnicity (versus white) IRR (adj.) 1.629 (
) Average [20 ] African American (versus white) IRR (adj.) 1.36 (1.04–1.77) Average [13 ] Maori/Pacific Islander (versus non-indigenous ethnicity) IRR (adj.) 1.64 (1.43–1.87) Good [34 ] Native Canadian (versus Caucasian) Time to first PE (not adj.)
Average [40 ] Black ethnicity (versus other) IRR (adj.) 1.37 (1.00–1.88) Average [32 ] White ethnicity (versus other) HR (adj.) 0.90 (0.39–2.35) Average [40 ] Asian (versus other) IRR (adj.) 0.89 (0.74–1.08) Average Age [12 ] Age per 10 years OR (adj.) 1.26 (1.07–1.48) Good [41 ] Age per 10 years IRR (adj.) 1.06 (1.01–1.10) Average [40 ] Age per 10 years IRR (adj.) 1.04 (1.01–1.08) Average [36 ] Age per year HR (adj.) 1.02 (1.01–1.03) Average [14 ] Age from 45–64 (versus 65–74) HR (adj.) 1.094 (1.007–1.188) Good [13 ] Age from 65–74 (versus 45–54) HR (adj.) 1.14 (1.06–1.22) Good [13 ] Age from 75-84 (versus 45–54) HR (adj.) 1.28 (1.15–1.43) Good [17 ] Age ≥ 65 years (versus <65 years) OR (adj.) 2.15 (1.09–4.24) Good [8 ] Age > 70 years (versus <70) Comp. of PET (not adj.)
Good [13 ] Age > 85 years (versus 45–54) HR (adj.) 1.94 (1.20–3.13) Good [14 ] Age < 45 years (versus 65–74) HR (adj.) 1.094 (1.007–1.188) Good [28 ] Younger age (NFI) IRR (adj.) N.R. (
) Average [32 ] Age ≥ 65 years (versus <65) HR (adj.) 0.80 (0.29–1.48) Average [14 ] Age ≥ 75 years (versus <75) HR (adj.) 1.071 (0.988–1.162) Good [39 ] Age 0–24.9 years (versus ≥65) HR (adj.) 0.90 (0.66–1.22) Average [39 ] Age 25–44.9 years (versus ≥65) HR (adj.) 0.83 (0.70–1.00) Average [39 ] Age 45–64.9 years (versus ≥65) HR (adj.) 0.88 (0.77–1.01) Average [10 ] Age per year HR (adj.) 0.99 (0.91–1.01) Good [7 ] Age < 40 years HR (adj.) 2.87 (0.80–10.30) Good [23 ] Age ≥ 60 years (versus <60 years) Time to first PE (not adj.)
Average [38 ] Age ≥ 65 years (versus <65 years) Time to first PE (not adj.)
= non-significantAverage Gender [12 ] Females (versus males) OR (adj.) 1.91 (1.20–3.01) Good [14 ] Females (versus males) HR (adj.) 0.968 (0.918–1.020) Good [17 ] Males (versus females) OR (adj.) 0.73 (0.44–1.21) Good [15 ] Males (versus females) HR (adj.) 0.95 (0.89–1.02) Good [38 ] Females (versus males) Time to first PE (not adj.)
= non-significantAverage [20 ] Females (versus males) IRR (adj.) 1.25 (0.63–1.01) Average Comorbidities [13 ] Chronic lung disease (versus no chronic lung disease) HR (adj.) 1.10 (1.03–1.18) Good [14 ] Congestive heart failure (versus no congestive heart failure) HR (adj.) 1.101 (1.034–1.172) Good [13 ] Coronary artery disease (versus no coronary artery disease) IRR (adj.) 1.06 (1.01–1.12) Good [15 ] Cardiovascular disease (versus no CVD) HR (adj.) 1.09 (1.04–1.17) Good [39 ] No hypertension (versus hypertension) HR (adj.) 0.76 (0.61–0.94) Average [17 ] Catheter exit site infection (versus none) OR (adj.) 2.63 (1.57–4.41) Good [32 ] Coronary artery disease (versus no coronary artery disease) HR (adj.) 0.60 (0.39–1.79) Average [10 ] History of cerebrovascular disease (versus no history) HR (adj.) 1.39 (0.82–2.35) Good [15 ] Cerebrovascular disease (versus no cerebrovascular disease) HR (adj.) 1.04 (0.95–1.14) Good [38 ] Cardiovascular disease (versus no cardiovascular disease) Time to first PE (not adj.)
= non-significantAverage Diabetes mellitus [14 ] Diabetes versus no diabetes HR (adj.) 1.131 (1.069–1.195) Good [10 ] Diabetes versus no diabetes HR (adj.) 1.5 (1.05–2.40) Good [9 ] Diabetes versus no diabetes HR (adj.) 1.64 (1.08–2.50) Good [28 ] Diabetes versus no diabetes IRR (adj.) 1.81 (
) Average [40 ] Diabetes in females (versus no diabetes) IRR (adj.) 1.27 (1.10–1.47) Average [13 ] Type 1 diabetes (versus no diabetes) HR (adj.) 1.24 (1.08–1.42) Good [13 ] Type 2 diabetes (versus no diabetes) HR (adj.) 1.1 (1.03–1.17) Good [35 ] Diabetes versus no diabetes Comp. of PET (not adj.)
= non-significantAverage [32 ] Diabetes versus no diabetes HR (adj.) 1.00 (0.46–2.17) Average [15 ] Diabetes versus no diabetes HR (adj.) 1.06 (0.94–1.18) Good [7 ] Diabetes versus no diabetes HR (adj.) 2.08 (0.88–4.95) Good [27 ] Diabetes versus no diabetes Time to first PE (not adj.)
Average [33 ] Diabetes versus no diabetes Time to first PE (not adj.)
Average [38 ] Diabetes versus no diabetes Time to first PE (not adj.)
= non-significantAverage [40 ] Diabetes in males (versus no diabetes) IRR (adj.) 0.99 (0.87–1.13) Average Underlying renal disease [24 ] Lupus nephritis (versus other) HR (adj.) HR N.R. (
) Average [40 ] Glomerulonephritis (versus other) IRR (adj.) 0.87 (0.75–1.00) Average Residual renal function [9 ] GFR per mL/min/1.73 m2 increase HR (adj.) 0.81 (0.74–0.88) Good
