Impairment and Differential Expression of PR3 and MPO on Peripheral Myelomonocytic Cells with Endothelial Properties in Granulomatosis with Polyangiitis

Figure 1

Flk-1⁺ and Flk-1⁺/CD133⁺ myelomonocytic cells (eEOCs) in patients with GPA, MPA, and SLE as compared to healthy controls. The percentages of circulating Flk-1⁺ cells (defined as all cells displaying endothelial characteristics) were lower in all patient groups (GPA, MPA, SLE) as compared to healthy controls. In contrast, total peripheral circulating eEOCs (Flk-1⁺/CD133⁺ cells) were not different between the four groups (bars show median).