Impairment and Differential Expression of PR3 and MPO on Peripheral Myelomonocytic Cells with Endothelial Properties in Granulomatosis with Polyangiitis

Figure 4

Percentages of PR3⁺/Flk-1⁺ cells. In order to evaluate PR3 expression on cells belonging to the endothelial lineage, peripheral myelomonocytic cells were stained for both, PR3 and Flk-1. As for the total myelomonocytic cell population, GPA patients showed higher percentages of PR3⁺/Flk-1⁺ cells than controls. Such differences were not detected between MPA or SLE and controls (bars show median).