Review Article

Achieving Salt Restriction in Chronic Kidney Disease

Table 2

Summary of adherence in key trials of sodium restriction.

StudyPopulation and designDurationFood provisionDietary educationMeasurement methodsFeedbackSodium goal
(mmol)
Actual intake
(mmol)

Pimenta et al. (2009) [4]n = 12
RCT-crossover
1 wkFullNil24 hr UNa (once), direct observationNil5046 + 27

Luik et al. (2002) [14]n = 38
RCT-crossover
1 wkNilPartial, individualized, at baseline only24 hr UNa (once)NS50Diabetics = 38 ± 13; Healthy = 45 ± 28

DASH-Sodium
Sacks et al. (2001) [64]
n = 375
RCT-crossover
4 wkFullPartial, individualized with follow-up, frequency NS24 hr UNa, daily diary, meal attendance, poststudy anonymous survey, plus monetary, and other incentivesDaily deviation record and met with dnLow 50 and Mod 100Low: 67 ± 46, 
Mod: 107 ± 52

Todd et al. (2010) [61]n = 24
RCT-crossover
4 wkNilWeekly, individualized, follow-up NS3d FR, recall, UNa:
Creatinine (after overnight fast)
24 hr recalls, met with dn (frequency NS)6078 ± 18

Gates et al. (2004) [60]n = 12
RCT-crossover
4 wkNilWeekly, individualized3d FR; 24 hr UNa (weekly)Met with dietitian6052 ± 4

Vogt et al. (2008) [8]n = 33
RCT-crossover
6 wkUnclearPartial, individualized, follow-up NS24 hr UNa (every 2 wk)Unclear5090 ± 10

Ireland et al. (2010) [65]n = 33
Randomized uncontrolled trial
8 wkNilGroup “Tick” versus Panel, not individualized, at baseline and wk 424 hr UNa, multiple pass
24 hr recall (at wk 4 and 8)
Unclear85Tick = 106 ± 47
FZANZ = 98 ± 50

Troyer et al. (2010) [59]n = 210
RCT-parallel
52 wkPartial
(1 group)
Partial, unclear if individualized, follow-up NS24 hr recall and 12 item FFQNil<50/1000 kcalMeals = 65 ± 24
Non = 67 ± 28 mmol/kcal

Sodium as mmol/day unless otherwise specified. Abbreviations: d: day, dn: dietitian, FFQ: food frequency questionnaire, FR: food records, hr: hour, mod: moderate, n: sample size, Na: sodium, NS: not specified, RCT: randomized controlled trial, U: urinary, wk: week.