Circulating Adiponectin Is Associated with Renal Function Independent of Age and Serum Lipids in West Africans

Table 3

Association between eGFR_MDRD or eGFR_CG and adiponectin using linear regression analyses in non-diabetic West Africans.

Dependent variable (log eGFRMDRD)							Dependent variable (log eGFRCG)
	Univariate model			Multivariate model			Univariate model			Multivariate model
	𝐵MDRD (SE)	BetaMDRD	𝑃MDRD	𝐵MDRD (SE)	BetaMDRD	𝑃MDRD	𝐵CG (SE)	BetaCG	𝑃CG	𝐵CG (SE)	BetaCG	𝑃CG
log10AdipoQ	−0.09 (0.02)	−0.18	<0.0001	−0.05 (0.02)	−0.10	0.004	−0.15 (0.02)	−0.26	<0.0001	−0.05 (0.02)	−0.09	0.001
Age	—	—	—	−0.003 (0.00)	−0.26	<0.0001	—	—	—	−0.005 (0.0)	−0.47	<0.0001
Sex	—	—	—	0.01 (0.01)	0.04	0.26	—	—	—	0.04 (0.01)	0.14	<0.0001
BMI	—	—	—	0.00 (0.001)	−0.01	0.79	—	—	—	0.01 (0.001)	0.33	<0.0001
HTN	—	—	—	0.008 (0.01)	0.03	0.42	—	—	—	0.007 (0.01)	0.02	0.44
Smoking	—	—	—	0.01 (0.02)	0.02	0.52	—	—	—	0.01 (0.02)	0.02	0.41
log10LDL-C	—	—	—	−0.15 (0.03)	−0.17	<0.0001	—	—	—	−0.13 (0.03)	−0.14	<0.0001
log10HDL-C	—	—	—	−0.08 (0.02)	−0.13	<0.0001	—	—	—	−0.07 (0.02)	−0.10	<0.0001
log10TG	—	—	—	−0.21 (0.03)	−0.26	<0.0001	—	—	—	−0.17 (0.02)	−0.19	<0.0001

𝐵_MDRD: unstandardized coefficient for GFR estimated by MDRD method; 𝐵_CG: unstandardized coefficient for GFR estimated by CG method.
Beta_MDRD: standardized coefficient for GFR estimated by MDRD method; Beta_CG: standardized coefficient for GFR estimated by MDRD method.
SE: standard error; AdipoQ: adiponectin.
HTN: hypertension; BMI: body mass index.
Adjusted R-square for univariate model = 0.03, adjusted R-square for multivariate model = 0.30 when eGFR_MDRD is the dependent variable.
Adjusted R-square for univariate model = 0.07; adjusted R-square for multivariate model = 0.56 when eGFR_CG is the dependent variable.
Significance level set at 0.05.