The Initial Vascular Access Type Contributes to Inflammation in Incident Hemodialysis Patients

Table 5

Mixed-effects model for IL-6 (log transformation) including all time points throughout the study (𝑛=662). In an adjusted analysis, IL-6 levels positively correlated with the presence of a TC, although this did not reach statistical significance (𝑃=0.07). There was an inverse correlation of IL-6 with absence of infection. IL-6: interleukin 6, TC: tunneled catheter, AVG: arteriovenous graft, AVF: arteriovenous fistula, DM: diabetes mellitus, CAD: coronary artery disease, HD: hemodialysis

Parameter	Estimate	95% confidence interval		𝑃
		Lower	Upper
Access type
AVF	Ref.
TC	0.15	−0.01	0.32	0.07
AVG	0.12	−0.10	0.35	0.28
CAD (no)	−0.17	−0.38	0.05	0.14
Sex (male)	0.08	−0.08	0.25	0.33
Infection (no)	−0.24	−0.44	−0.04	0.02
Age	0.00	0.00	0.01	0.67
Race
Hispanic	Ref.
African American	0.10	−0.06	0.27	0.21
Caucasian	0.02	−0.30	0.34	0.89
DM (no)	−0.08	−0.25	0.08	0.32
HD (no)	−0.01	−0.13	0.10	0.85
Access thrombosis (no)	0.09	−0.09	0.26	0.35
Number of days after access insertion
7 days	0.05	−0.16	0.27	0.61
30 days	−0.12	−0.33	0.09	0.25
90 days	−0.16	−0.37	0.04	0.12
180 days	−0.24	−0.43	−0.05	0.01
270 days	−0.14	−0.31	0.02	0.09
365 days	Ref.