The Initial Vascular Access Type Contributes to Inflammation in Incident Hemodialysis Patients

Table 6

Mixed-effects model for IP-10 (log transformation) including all time points throughout the study (𝑛=662). In an adjusted analysis, IP-10 levels positively correlated with the presence of a TC and AVG, although the latter did reach statistical significance, (𝑃=0.07). IP-10 levels were also significantly associated with male sex. There was an inverse correlation of IP-10 with DM and African American or Caucasian race. IP-10: interferon-γ-induced protein, TC: tunneled catheter, AVG: arteriovenous graft, AVF: arteriovenous fistula, DM: diabetes mellitus, CAD: coronary artery disease, HD: hemodialysis

Parameter	Estimate	95% Confidence Interval		𝑃
		Lower	Upper
Access type
AVF	Ref.
TC	0.26	0.03	0.49	0.03
AVG	0.30	−0.03	0.63	0.07
CAD (no)	0.17	−0.24	0.58	0.41
Sex (male)	0.43	0.12	0.74	0.01
Age	0.000	−0.01	0.01	0.65
Race
Hispanic	Ref.
African American	−0.30	−0.60	0.01	0.01
Caucasian	−0.64	−1.25	−0.04	0.04
DM (no)	−0.38	−0.70	−0.05	0.02
Infection (no)	−0.14	−0.38	0.10	0.27
Access thrombosis (no)	0.10	−0.09	0.29	0.31
Number of days after access insertion
7 days	0.08	−0.17	0.34	0.52
30 days	0.06	−0.19	0.32	0.64
90 days	0.02	−0.22	0.26	0.85
180 days	−0.10	−0.29	0.09	0.31
270 days	−0.05	−0.21	0.11	0.51
365 days	Ref.