Effect of Intensive Blood Pressure Control on Cardiovascular Remodeling in Hypertensive Patients with Nephrosclerosis

Table 2

Association of CV composite outcome with blood pressure indices.

BP index	Time period for blood pressure assessment	RR (95% CI)	P  value
Diastolic BP; (per 10 mmHg)	Baseline	1.07 (0.94–1.21)	0.30
	Mean follow-up	1.20 (0.97–1.49)	0.09
Systolic BP; (per 10 mmHg)	Baseline	1.09 (1.01–1.17)	0.02
	Mean follow-up	1.30 (1.15–1.48)	<0.01
Pulse pressure; (per 10 mmHg)	Baseline	1.12 (1.02–1.23)	0.02
	Mean follow-up	1.28 (1.11–1.47)	<0.01

Association of CV composite outcome with BP indices after adjustment for 11 baseline factors: age, gender, total cholesterol, HDL cholesterol,  uric acid, BMI, GFR, HCT (%), smoking status, education, and log transformed urine protein/creatinine ratio. Analyses of baseline BP indices were also adjusted for randomized treatment assignment. CV composite outcome was defined as a CV death or the first occurrence of a CV hospitalization. Sample sizes were 1080 (with 147 events for the CV composite) for analyses of baseline BP indices and 1052 (with 143 events for the CV composite) for analyses of mean follow-up values of BP indicates.