Research Article

Does the RIFLE Classification Improve Prognostic Value of the APACHE II Score in Critically Ill Patients?

Table 4

Comparative analysis of discrimination and calibration of APACHE II in predicting mortality in the ICU alone and when combined with the RIFLE score calculated within 24 hours after ICU admission and on the Day of AKI.

Score DiscriminationCalibration
Area under
the ROC curve
CI 95% PP GOF PP

APACHE II 24 h 0.74 0.66–0.81 0.001 9.6 0.289
APACHE II + RIFLE 24 h 0.77 0.70–0.84 0.001
APACHE II in
RIFLE-1
0.750.68–0.800.001120.156
APACHE II + RIFLE-10.800.74–0.860.001

ROC: receiver operating characteristic; IC: confidence interval; GOF: goodness of fit; APACHE II: Acute Physiology and Chronic Health Evaluation version II; RIFLE 24 h: RIFLE-Risk, Injury, Failure, Loss, End defined within 24 hours of ICU stay; RIFLE-1 Risk, Injury, Failure, Loss, End set on the day of AKI during ICU stay.