Gene Expression Changes in Venous Segment of Overflow Arteriovenous Fistula

Table 4

Statistically overrepresented GO terms in the biological process category (𝑃<0.001).

Biological process
GO accession (with AmiGO link)	GO term	Corrected 𝑃 value	Count in selection	% count in selection	Count in total	% count in total
GO:0032502	Developmental process	2.100𝐸−11	77	29.8	3077	17.9
GO:0007275	Multicellular organismal development	1.340𝐸−10	67	26.0	2810	16.3
GO:0010033	Response to organic substance	3.530𝐸−10	40	15.5	698	4.1
GO:0001568	Blood vessel development	9.230𝐸−10	21	8.1	231	1.3
GO:0048514	Blood vessel morphogenesis	1.250𝐸−09	19	7.4	198	1.1
GO:0001944	Vasculature development	1.250𝐸−09	21	8.1	238	1.4
GO:0048545	Response to steroid hormone stimulus	1.360𝐸−09	23	8.9	183	1.1
GO:0001525	Angiogenesis	2.930𝐸−09	18	7.0	139	0.8
GO:0009653	Anatomical structure morphogenesis	4.930𝐸−09	30	11.6	1125	6.5
GO:0016265	Death	5.110𝐸−09	39	15.1	663	3.8
GO:0048646	Anatomical structure formation involved in morphogenesis	5.950𝐸−09	18	7.0	306	1.8
GO:0008219	Cell death	1.280𝐸−08	37	14.3	658	3.8
GO:0042221	Response to chemical stimulus	1.280𝐸−08	53	20.5	1264	7.3
GO:0048856	Anatomical structure development	1.320𝐸−08	42	16.3	2437	14.1
GO:0006950	Response to stress	2.080𝐸−08	51	19.8	1642	9.5
GO:0048731	System development	3.600𝐸−08	38	14.7	2284	13.3
GO:0032570	Response to progesterone stimulus	7.370𝐸−08	9	3.5	21	0.1
GO:0006915∣GO:0008632	Apoptosis	1.340𝐸−07	31	12.0	541	3.1
GO:0012501∣GO:0016244	Programmed cell death	1.900𝐸−07	31	12.0	549	3.2
GO:0042981	Regulation of apoptosis	2.470𝐸−07	35	13.6	796	4.6
GO:0032501∣GO:0050874	Multicellular organismal process	3.190𝐸−07	70	27.1	4154	24.1
GO:0043067∣GO:0043070	Regulation of programmed cell death	3.190𝐸−07	35	13.6	804	4.7
GO:0010941	Regulation of cell death	3.310𝐸−07	35	13.6	807	4.7
GO:0009887	Organ morphogenesis	3.510𝐸−07	26	10.1	685	4.0
GO:0009628	Response to abiotic stimulus	5.270𝐸−07	16	6.2	357	2.1
GO:0009725	Response to hormone stimulus	5.390𝐸−07	23	8.9	358	2.1
GO:0048519∣GO:0043118	Negative regulation of biological process	6.290𝐸−07	39	15.1	1756	10.2
GO:0009719	Response to endogenous stimulus	7.450𝐸−07	24	9.3	391	2.3
GO:0009605	Response to external stimulus	7.730𝐸−07	32	12.4	869	5.0
GO:0048513	Organ development	1.510𝐸−06	34	13.2	1682	9.8
GO:0009607	Response to biotic stimulus	2.160𝐸−06	23	8.9	385	2.2
GO:0070482	Response to oxygen levels	3.460𝐸−06	14	5.4	137	0.8
GO:0009266	Response to temperature stimulus	3.950𝐸−06	9	3.5	86	0.5
GO:0050896∣GO:0051869	Response to stimulus	6.040𝐸−06	89	34.5	3356	19.5
GO:0048523∣GO:0051243	Negative regulation of cellular process	8.220𝐸−06	38	14.7	1606	9.3
GO:0009408∣GO:0006951	Response to heat	8.220𝐸−06	9	3.5	61	0.4
GO:0006928	Cellular component movement	1.200𝐸−05	14	5.4	450	2.6
GO:0050793	Regulation of developmental process	1.590𝐸−05	8	3.1	670	3.9
GO:0048869	Cellular developmental process	1.600𝐸−05	24	9.3	1641	9.5
GO:0022603	Regulation of anatomical structure morphogenesis	2.530𝐸−05	5	1.9	228	1.3
GO:0051239	Regulation of multicellular organismal process	2.860𝐸−05	7	2.7	924	5.4
GO:0007565	Female pregnancy	3.100𝐸−05	13	5.0	104	0.6
GO:0030154	Cell differentiation	4.450𝐸−05	24	9.3	1576	9.1
GO:0042127	Regulation of cell proliferation	4.830𝐸−05	29	11.2	773	4.5
GO:0001666	Response to hypoxia	6.420𝐸−05	14	5.4	131	0.8
GO:0008284	Positive regulation of cell proliferation	7.720𝐸−05	16	6.2	410	2.4
GO:0048522∣GO:0051242	Positive regulation of cellular process	7.720𝐸−05	34	13.2	1806	10.5
GO:0051789	Response to protein stimulus	8.360𝐸−05	11	4.3	96	0.6
GO:0048518∣GO:0043119	Positive regulation of biological process	9.260𝐸−05	35	13.6	1982	11.5
GO:0043627	Response to estrogen stimulus	1.000𝐸−04	12	4.7	98	0.6
GO:0009991	Response to extracellular stimulus	1.000𝐸−04	6	2.3	204	1.2
GO:0042493∣GO:0017035	Response to drug	1.770𝐸−04	17	6.6	213	1.2
GO:0043066	Negative regulation of apoptosis	1.790𝐸−04	19	7.4	345	2.0
GO:0043069∣GO:0043072	Negative regulation of programmed cell death	2.200𝐸−04	19	7.4	350	2.0
GO:0051384	Response to glucocorticoid stimulus	2.200𝐸−04	10	3.9	70	0.4
GO:0050789∣GO:0050791	Regulation of biological process	2.440𝐸−04	109	42.2	7200	41.8
GO:0060548	Negative regulation of cell death	2.570𝐸−04	19	7.4	354	2.1
GO:0051707∣GO:0009613∣GO:0042828	Response to other organism	2.770𝐸−04	17	6.6	300	1.7
GO:0040011	Locomotion	2.800𝐸−04	16	6.2	415	2.4
GO:0009611∣GO:0002245	Response to wounding	2.800𝐸−04	21	8.1	507	2.9
GO:0031960	Response to corticosteroid stimulus	3.860𝐸−04	10	3.9	75	0.4
GO:0050794∣GO:0051244	Regulation of cellular process	4.070𝐸−04	108	41.9	6938	40.3
GO:0014070	Response to organic cyclic substance	4.200𝐸−04	12	4.7	114	0.7
GO:0051128	Regulation of cellular component organization	5.900𝐸−04	6	2.3	466	2.7
GO:0065007	Biological regulation	7.620𝐸−04	109	42.2	7592	44.1
GO:0051704∣GO:0051706	Multiorganism process	7.900𝐸−04	27	10.5	706	4.1
GO:0031099	Regeneration	8.770𝐸−04	6	2.3	65	0.4
GO:0007610	Behavior	9.680𝐸−04	12	4.7	449	2.6