Research Article

Gene Expression Changes in Venous Segment of Overflow Arteriovenous Fistula

Table 7

Pathway analysis results.

Pathway nameLS_vs_control

Alpha6 beta4 integrin signaling pathway0.793
Androgen receptor signaling pathway0.528
Apoptosis mechanisms0.124
B-cell receptor signaling pathway0.023
G1 to S cell cycle control1
Cell cycle0.487
Delta-Notch signaling pathway0.226
DNA replication1
EGFR1 signaling pathway0.856
FAS pathway and stress induction of HSP regulation1
Focal Adhesion0.003
G13 signaling pathway 0.269
G protein signaling pathways0.258
Hedgehog signaling pathway1
Apoptosis modulation by HSP701
Id signaling pathway1
IL-1 signaling pathway1
IL-2 signaling pathway0.327
IL-3 signaling pathway0.371
IL-4 signaling pathway0.589
IL-5 signaling pathway0.576
IL-6 signaling pathway1
IL-7 signaling pathway0.498
IL-9 signaling pathway1
Human insulin signaling0.387
Integrin-mediated cell adhesion0.363
Kit receptor signaling pathway0.051
MAPK cascade1
MAPK signaling pathway0.011
mRNA processing (Homo sapiens)0.014
Notch signaling pathway0.191
Ovarian infertility genes1
p38 MAPK signaling pathway (BioCarta)0.108
Regulation of actin cytoskeleton0.834
Eukaryotic transcription initiation0.511
Signal transduction of S1P0.384
Signaling of hepatocyte growth factor receptor1
T cell receptor signaling pathway0.243
TGF-beta receptor signaling pathway0.095
TGF beta signaling pathway0
TNF-alpha/NF- B signaling pathway0.752
Translation factors0.368
Wnt signaling pathway0.15
Wnt signaling pathway0.051
Acetylcholine synthesis1
Alanine and aspartate metabolismā€”
Biogenic amine synthesis1
Cholesterol biosynthesis0.644
Eicosanoid synthesis1
Electron transport chain0.013
Fatty acid beta oxidation 10.403
Fatty acid beta oxidation 21
Fatty acid beta oxidation 31
Beta oxidation meta MAPP0.264
Fatty acid omega oxidation0.687
Fatty acid biosynthesis0.426
Glucocorticoid and mineralcorticoid metabolism1
Glutathione metabolism0.399
Glycogen metabolism0.261
Glycolysis and gluconeogenesis0.235
Heme biosynthesis1
TCA cycle0.24
Mitochondrial LC-fatty acid beta-oxidation0.635
Nuclear receptors in lipid metabolism and toxicity0.389
Nucleotide metabolism0.622
Pentose phosphate pathway1
Prostaglandin synthesis and regulation1
Statin pathway (PharmGKB)1
Steroid biosynthesis1
Synthesis and degradation of ketone bodies1
Triacylglyceride synthesis0.419
Tryptophan metabolism0.501
Beta oxidation of unsaturated fatty acids1
Urea cycle and metabolism of amino groupsā€”
GPCRs, class A rhodopsin-like0.317
GPCRs, class B secretin-like1
GPCRs, class C metabotropic glutamate, pheromone1
GPCRs, other1
Matrix metalloproteinases0.652
Monoamine GPCRs1
Nuclear receptors1
Nucleotide GPCRs1
Peptide GPCRs0.081
Cytoplasmic ribosomal proteins0.025
Small ligand GPCRs1
ACE inhibitor pathway (Homo sapiens)0.254
Adipogenesis human0.101
Blood clotting cascade0.155
Calcium regulation in the cardiac cell0.431
Circadian exercise0.754
Complement activation and classical pathway0.646
Complement activation and classical pathway0.022
Cytokines and inflammatory response (BioCarta)0
Hypertrophy model0
Inflammatory response pathway0.054
Irinotecan pathway (Homo sapiens)0.685
Oxidative stress0.402
Proteasome degradation0.278
Myometrial relaxation and contraction pathways0
Striated muscle contraction0.427