Research Article

Expression of Tight Junction Protein Claudin-1 in Human Crescentic Glomerulonephritis

Table 1

Clinical features of patients in this study.

NoAge (years)SexDiseaseCr (mg/dL)Hematuria (/ L)UP/UCr (g/gCre)U- 2MG ( g/L)CRP (mg/dL)Treatment

125FIgA nephropathy10.43813.8315100.07PSL, HD, LKT
257MIgA nephropathy5.41497.6131850.35mPSL, oral PSL
332MIgA nephropathy0.91402.595.60.11mPSL, oral PSL
420FIgA nephropathy1.0608.248.60.06mPSL, oral PSL
538FIgA nephropathy1.717083.49378.55.09mPSL, oral PSL
620FPurpura nephritis0.71621.1182.10.06None
739FPurpura nephritis0.72122.174.20.06Oral PSL
863MMPO-AAV9.01400.5223703.43mPSL, oral PSL
939MMPO-AAV13.12083.8226.813.37 mPSL, oral PSL
1061MMPO-AAV2.91300.88471.92.82mPSL, oral PSL
1168MMPO-AAV2.310303.83064.33.83mPSL, oral PSL
1277MMPO-AAV3.12433.390.65.73mPSL, oral PSL
1370MMPO-AAV2.31931.3164.95.37mPSL, oral PSL
1471MMPO-AAV9.14570.4476832.75mPSL, oral PSL
1564MPR3-AAV2.82851.7523.323.55 mPSL, CY
1664MAnti-GBM RPGN15.44202.4701216.40mPSL, PE, HD
1763FLupus nephritis (IV + V)1.32817.0337.22.03mPSL

Cr: creatinine; CY: cyclophosphamide; GBM: glomerular basement membrane; HD: hemodialysis; IgA: immunoglobulin A; LKT: living kidney transplantation; MPO-AAV: myeloperoxidase anti-neutrophil cytoplasmic antibody associated vasculitis; mPSL: methyl-prednisolone pulse therapy; PE: plasma exchange; PR3-AAV: proteinase 3 anti-neutrophil cytoplasmic antibody associated vasculitis; PSL: prednisolone; RPGN: rapidly progressive glomerulonephritis; UP/UCr: urine protein to creatinine ratio; U- 2MG: urinary beta2-microglobulin.