International Journal of Nephrology

Research Article

Soluble Fas and the −670 Polymorphism of Fas in Lupus Nephritis

Table 1

Genotype and alleles frequencies of the −670 A/G Fas polymorphism in SLE and LN patients and HS.  
 SLE ( = 43)  
% ()		LN ( = 24)  
% ()		HS ( = 54)  
% ()		 value
Genotype          
 A/A  33 (14)  29 (7)  52 (28)   = 0.22  
 A/G  30 (13)  38 (9)  22 (12)   
 G/G37 (16)33 (8)26 (14) 
Allele    
 A48 (41)48 (23)63 (68 = 0.03*  
 G  52 (45  52 (25)  37 (40)  OR = 1.86  
95% CI = 1.007–3.45
 A/A + A/G   63 (27)   67 (16)   74 (40)   
 GG  37 (16)  33 (8)  26 (14)     = 0.23  
 AA  33 (14)  29 (7)  52 (28 = 0.05*  
 A/G + G/G67 (2971 (17)48 (26)OR = 2.23  
95% CI = 0.90–5.6
LN: lupus nephritis; SLE: systemic lupus erythematosus; HS: healthy subjects; HS versus SLE; SLE versus HS; HS versus SLE; SLE versus HS. A value <0.05 is significant.