Associates of Cardiopulmonary Arrest in the Perihemodialytic Period
Table 2
Logistic models of peridialytic cardiopulmonary arrest predictors in the matched primary analysis.
Model 1
Model 2
Model 3
Model 4
(univariate)
(full multivariate)
(stepwise)
(Model 3 + quadratics)
OR (95% CI)
OR (95% CI)
OR (95% CI)
OR (95% CI)
Body mass index (kg/m²)
<18.5
1.66* (1.05–2.65)
1.95* (1.10–3.44)
2.03*** (1.37–3.00)
1.95*** (1.32–2.89)
18.6–25
1 (ref.)
1 (ref.)
—
—
25.1–29.9
0.81 (0.62–1.04)
0.85 (0.61–1.19)
—
—
≥30
0.84 (0.66–1.06)
0.80 (0.52–1.23)
—
—
Coronary artery disease
1.27** (1.09–1.49)
1.41*** (1.15–1.72)
1.39*** (1.14–1.70)
1.38** (1.13–1.68)
Heart failure
1.25** (1.08–1.45)
1.24* (1.02–1.51)
1.24* (1.03–1.51)
1.27* (1.05–1.54)
Vintage (per 100 days)
0.99* (0.98–1.00)
1.00 (0.99–1.01)
—
—
Catheter vascular access
1.61**** (1.39–1.86)
1.00 (0.82–1.22)
—
—
EDW (kg)
1.00 (0.99–1.00)
1.00 (1.00–1.01)
—
—
Percent IDWG (%)
1.01** (1.004–1.02)
1.00 (0.96–1.04)
—
—
TT shortened > 10 minutes (yes/no)
1.32** (1.10–1.58)
1.14 (0.89–1.45)
—
—
Missed treatment due to hospitalization (yes/no)
1.94**** (1.65–2.28)
1.48*** (1.20–1.84)
1.48*** (1.20–1.82)
1.45*** (1.18–1.80)
Missed treatment due to unexcused absence (yes/no)
1.05 (0.85–1.28)
1.01 (0.77–1.33)
—
—
Dialysate sodium (mEq/L)
0.99 (0.96–1.02)
1.01 (0.97–1.04)
—
—
Dialysate calcium (mEq/L)
—
—
<2.3
1.01 (0.82–1.25)
1.07 (0.83–1.37)
—
—
2.3–2.5
1.00 (ref.)
1.00 (ref.)
—
—
>2.5
0.60 (0.33–1.10)
0.64 (0.32–1.30)
—
—
Dialysate potassium (mEq/L)
1
1.26 (0.77–2.06)
1.72* (0.99–2.99)
1.73** (1.12–2.68)
1.89** (1.23–2.90)
2
1.00 (ref.)
1.00 (ref.)
—
—
>2
1.00 (0.79–1.28)
0.83 (0.61–1.12)
—
—
Dialysate buffer (mEq/L)
—
—
<41
1.01 (0.75–1.35)
0.95 (0.67–1.34)
—
—
41–45
1.00 (ref.)
1.00 (ref.)
—
—
>45
0.79 (0.55–1.16)
0.77 (0.49–1.19)
—
—
ESA per treatment (per 1000 u)
1.04**** (1.03–1.05)
1.01* (1.00–1.02)
1.01* (1.00–1.03)
1.01* (1.00–1.02)
eKt/V
0.73** (0.59–0.91)
0.93 (0.72–1.22)
—
—
Albumin (g/dL)
0.43**** (0.38–0.50)
0.65*** (0.51–0.81)
0.65**** (0.53–0.81)
0.68*** (0.55–0.85)
Hemoglobin (g/dL)
0.73**** (0.69–0.77)
0.81**** (0.76–0.88)
0.82**** (0.76–0.88)
0.81**** (0.75–0.87)
Phosphorus (mg/dL)
0.93*** (0.89–0.97)
1.01 (0.95–1.07)
—
—
Calcium (mg/dL)
0.84*** (0.77–0.92)
1.17* (1.02–1.33)
1.16* (1.02–1.32)
1.17* (1.04–1.33)
Potassium (mEq/L)
0.78**** (0.71–0.86)
0.85* (0.74–0.98)
—
—
Ferritin (per 100 ng/mL)
1.00 (0.98–1.01)
0.99 (0.97–1.01)
—
—
Bicarbonate (mEq/L)
1.03* (1.01–1.05)
0.99 (0.96–1.01)
—
—
nPCR (g/kg/day)
0.45**** (0.34–0.60)
0.69 (0.47–1.00)
0.62** (0.45–0.88)
0.53*** (0.38–0.75)
nPCR2 (g/kg/day)
—
—
—
1.99** (1.24–3.20)
c-statistic
—
0.68
0.67
0.68
; ; ; . For independent variables with more than 2 categories, values and confidence intervals were adjusted with multiple comparisons using Bonferroni method. OR, odds ratio; CI, confidence interval; IDWG, interdialytic weight gain; TT, treatment time; nPCR, normalized protein catabolic rate; ESA, erythropoietin stimulating agent; and EDW, estimated dry weight.
