Associates of Cardiopulmonary Arrest in the Perihemodialytic Period
Table 5
Logistic models of predictors of peridialytic cardiopulmonary arrest in two matched secondary analyses.
Variable
CPA cases versus control-1s
CPA cases versus control-2s
Model 1
Model 4
Model 1
Model 4
(univariate)
(stepwise + quadratics)
(univariate)
( stepwise + quadratics)
OR (95% CI)
OR (95% CI)
OR (95% CI)
OR (95% CI)
Body mass index (kg/m2)
<18.5
2.24** (1.18–4.24)
3.52**** (1.98–6.26)
1.03 (0.62–1.72)
—
18.6–25
1 (ref.)
—
—
—
25.1–29.9
0.66*** (0.49–0.88)
—
1.09 (0.82–1.45)
—
≥30
0.63**** (0.48–0.83)
0.75* (0.60–0.95)
1.08 (0.83–1.42)
—
Coronary artery disease
1.39*** (1.16–1.67)
1.36* (1.07–1.73)
1.11 (0.93–1.33)
—
Heart failure
1.56**** (1.31–1.85)
1.57**** (1.25–1.99)
1.00 (0.85–1.19)
—
Vintage (per 100 days)
1.00 (1.00-1.00)
1.01** (1.00–1.02)
1.00* (1.00-1.00)
—
Catheter vascular access
2.05**** (1.73–2.42)
—
1.24* (1.06–1.47)
—
Percent IDWG
0.99 (0.94–1.06)
—
0.94 (0.89–0.99)*
—
TT shortened > 10 minutes (yes/no)
1.11 (0.82, 1.51)
—
1.03 (0.80–1.33)
—
Missed treatment due to hospitalization (yes/no)
2.02****(1.54, 2.65)
2.13**** (1.63, 2.79)
1.25 (0.99, 1.56)
—
Missed treatment due to unexcused absence (yes/no)
1.08 (0.78, 1.50)
—
0.82 (0.62, 1.09)
—
Dialysate sodium (mEq/L)
1.00 (0.96–1.04)
—
0.99 (0.95–1.02)
—
Dialysate calcium (mEq/L)
—
<2.3
1.03 (0.81–1.31)
—
1.05 (0.83–1.35)
—
2.3–2.5
1.00 (ref.)
—
1.00 (ref.)
—
>2.5
0.78 (0.40–1.54)
—
0.53 (0.28–1.01)
—
Dialysate potassium (mEq/L)
1
1.59 (0.87–2.91)
2.67*** (1.54–4.63)
1.19 (0.67–2.11)
—
2
1.00 (ref.)
—
1.00 (ref.)
—
>2
1.05 (0.80–1.38)
—
0.89 (0.68–1.17)
—
Dialysate buffer (mEq/L)
—
<41
1.04 (0.74–1.45)
—
0.89 (0.64–1.24)
—
41–45
1.00 (ref.)
—
1.00 (ref.)
—
>45
1.04 (0.67–1.60)
—
0.93 (0.60–1.42)
—
ESA per treatment (per 1000 u)
1.007**** (1.006–1.008)
1.04**** (1.02–1.06)
1.00 (1.00-1.00)
—
eKt/V
0.64** (0.49–0.84)
—
0.95 (0.80–1.12)
—
Albumin (g/dL)
0.21**** (0.17–0.25)
0.40**** (0.30–0.52)
1.01 (0.87–1.17)
—
Hemoglobin (g/dL)
0.67**** (0.63–0.72)
0.78**** (0.72–0.86)
0.87**** (0.83–0.92)
0.87**** (0.82–0.92)
Phosphorus (mg/dL)
0.92** (0.88–0.97)
—
0.96 (0.91–1.00)
—
Calcium (mg/dL)
0.72**** (0.65–0.80)
—
1.04 (0.95–1.15)
1.13* (1.02–1.25)
Potassium (mEq/L)
0.75**** (0.67–0.85)
—
0.82*** (0.74–0.92)
0.84** (0.75–0.93)
Ferritin (per 100 ng/ml)
1.00 (0.98–1.02)
—
0.98* (0.97–1.00)
0.98* (0.97–1.00)
Bicarbonate (mEq/L)
1.00 (1.00–1.05)
—
1.02 (0.99–1.04)
—
nPCR (g/kg/day)
0.25**** (0.18–0.34)
0.43**** (0.28–0.64)
0.79 (0.59–1.04)
—
nPCR2 (g/kg/day)
—
2.22* (1.18–4.19)
—
—
c-statistic
—
0.77
—
0.58
; ; ; . For independent variables with more than 2 categories, values and confidence intervals were adjusted with multiple comparisons using Bonferroni method. OR, odds ratio; CI, confidence interval; IDWG, interdialytic weight gain; TT, treatment time; nPCR, normalized protein catabolic rate; ESA, erythropoietin stimulating agent; and EDW, estimated dry weight.