International Journal of Nephrology

Research Article

Associates of Cardiopulmonary Arrest in the Perihemodialytic Period

Table 5

Logistic models of predictors of peridialytic cardiopulmonary arrest in two matched secondary analyses.


Variable	CPA cases versus control-1s		CPA cases versus control-2s
	Model 1	Model 4	Model 1	Model 4
	(univariate)	(stepwise + quadratics)	(univariate)	( stepwise + quadratics)
	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)

Body mass index (kg/m²)
<18.5	2.24^** (1.18–4.24)	3.52^**** (1.98–6.26)	1.03 (0.62–1.72)	—
18.6–25	1 (ref.)	—	—	—
25.1–29.9	0.66^*** (0.49–0.88)	—	1.09 (0.82–1.45)	—
≥30	0.63^**** (0.48–0.83)	0.75^* (0.60–0.95)	1.08 (0.83–1.42)	—
Coronary artery disease	1.39^*** (1.16–1.67)	1.36^* (1.07–1.73)	1.11 (0.93–1.33)	—
Heart failure	1.56^**** (1.31–1.85)	1.57^**** (1.25–1.99)	1.00 (0.85–1.19)	—
Vintage (per 100 days)	1.00 (1.00-1.00)	1.01^** (1.00–1.02)	1.00^* (1.00-1.00)	—
Catheter vascular access	2.05^**** (1.73–2.42)	—	1.24^* (1.06–1.47)	—
Percent IDWG	0.99 (0.94–1.06)	—	0.94 (0.89–0.99)^*	—
TT shortened > 10 minutes (yes/no)	1.11 (0.82, 1.51)	—	1.03 (0.80–1.33)	—
Missed treatment due to hospitalization (yes/no)	2.02^****(1.54, 2.65)	2.13^**** (1.63, 2.79)	1.25 (0.99, 1.56)	—
Missed treatment due to unexcused absence (yes/no)	1.08 (0.78, 1.50)	—	0.82 (0.62, 1.09)	—
Dialysate sodium (mEq/L)	1.00 (0.96–1.04)	—	0.99 (0.95–1.02)	—
Dialysate calcium (mEq/L)		—
<2.3	1.03 (0.81–1.31)	—	1.05 (0.83–1.35)	—
2.3–2.5	1.00 (ref.)	—	1.00 (ref.)	—
>2.5	0.78 (0.40–1.54)	—	0.53 (0.28–1.01)	—
Dialysate potassium (mEq/L)
1	1.59 (0.87–2.91)	2.67^*** (1.54–4.63)	1.19 (0.67–2.11)	—
2	1.00 (ref.)	—	1.00 (ref.)	—
>2	1.05 (0.80–1.38)	—	0.89 (0.68–1.17)	—
Dialysate buffer (mEq/L)		—
<41	1.04 (0.74–1.45)	—	0.89 (0.64–1.24)	—
41–45	1.00 (ref.)	—	1.00 (ref.)	—
>45	1.04 (0.67–1.60)	—	0.93 (0.60–1.42)	—
ESA per treatment (per 1000 u)	1.007^**** (1.006–1.008)	1.04^**** (1.02–1.06)	1.00 (1.00-1.00)	—
eKt/V	0.64^** (0.49–0.84)	—	0.95 (0.80–1.12)	—
Albumin (g/dL)	0.21^**** (0.17–0.25)	0.40^**** (0.30–0.52)	1.01 (0.87–1.17)	—
Hemoglobin (g/dL)	0.67^**** (0.63–0.72)	0.78^**** (0.72–0.86)	0.87^**** (0.83–0.92)	0.87^**** (0.82–0.92)
Phosphorus (mg/dL)	0.92^** (0.88–0.97)	—	0.96 (0.91–1.00)	—
Calcium (mg/dL)	0.72^**** (0.65–0.80)	—	1.04 (0.95–1.15)	1.13^* (1.02–1.25)
Potassium (mEq/L)	0.75^**** (0.67–0.85)	—	0.82^*** (0.74–0.92)	0.84^** (0.75–0.93)
Ferritin (per 100 ng/ml)	1.00 (0.98–1.02)	—	0.98^* (0.97–1.00)	0.98^* (0.97–1.00)
Bicarbonate (mEq/L)	1.00 (1.00–1.05)	—	1.02 (0.99–1.04)	—
nPCR (g/kg/day)	0.25^**** (0.18–0.34)	0.43^**** (0.28–0.64)	0.79 (0.59–1.04)	—
nPCR² (g/kg/day)	—	2.22^* (1.18–4.19)	—	—

c-statistic	—	0.77	—	0.58

; ; ; .
For independent variables with more than 2 categories, values and confidence intervals were adjusted with multiple comparisons using Bonferroni method.
OR, odds ratio; CI, confidence interval; IDWG, interdialytic weight gain; TT, treatment time; nPCR, normalized protein catabolic rate; ESA, erythropoietin stimulating agent; and EDW, estimated dry weight.