Childhood Nephrotic Syndrome Management and Outcome: A Single Center Retrospective Analysis
Table 2
Outpatient management and adherence patterns by nephrotic syndrome classification.
Management
SSNS
FRNS/SDNS
SRNS
Total
Mean clinic visits per year (SD)
2.59 (1.1)
4.33 (1.7)
4.71 (1.7)
3.7 (2.0)
Immunosuppressive treatment
Corticosteroids only
23 (100)
19 (40)
4 (25)
46 (53)
Mycophenolate mofetil
0 (0)
24 (50)
6 (38)
30 (34)
Cyclophosphamide
0 (0)
7 (15)
2 (13)
9 (10)
Tacrolimus
0 (0)
7 (15)
3 (19)
10 (11)
Cyclosporine
0 (0)
2 (4)
8 (50)
10 (11)
>1 agents in addition to corticosteroids
0 (0)
10 (21)
4 (25)
14 (16)
Medication adherence
Adherent
18 (78)
24 (50)
8 (50)
50 (57)
Nonadherent
5 (22)
24 (50)
8 (50)
37 (43)
Clinic follow-up adherence
Adherent
15 (65)
35 (73)
9 (56)
60 (70)
Nonadherent
8 (35)
13 (27)
7 (44)
28 (32)
Total
Urine monitoring
Adherent
15 (65)
24 (50)
N/A
39 (55)
Nonadherent
8 (35)
24 (50)
N/A
32 (45)
Data are presented as the number of patients with the percentage in parenthesis or mean and standard deviation in parenthesis. FRNS, frequently relapsing nephrotic syndrome; MCD, minimal change disease; FSGS, focal segmental glomerulosclerosis; SD, standard deviation; SDNS, steroid-dependent nephrotic syndrome; SRNS, steroid-resistant nephrotic syndrome; SSNS, steroid-sensitive and infrequently relapsing nephrotic syndrome.
