Analysis of T Cell Subsets in Adult Primary/Idiopathic Minimal Change Disease: A Pilot Study

Figure 2

(a) Percentage of cortex infiltration of CD8⁺ T cells, CD4⁺ T cells, and CD19⁺ B cells in kidney tissue of 9 patients with primary MCD. (b) Cell densities of the infiltrating Foxp3⁺ Treg cells, IL-17⁺ Th17 cells, and granzyme B⁺ cytotoxic cells in kidney tissue of these primary MCD patients. (c) Ratios of the cell densities of Th17 cells over Foxp3⁺ Treg cells and cytotoxic cells over Treg cells, infiltrating kidney tissue of primary MCD patients (the horizontal black line indicates the arbitrary ratio reference value of 1; the red arrows indicate the direction of the ratios, increased or decreased). Cells were detected by immunohistochemistry, and the median percentages, cell densities, and their ratios are reported.

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