Research Article
Clinical Utility of Urinary β2-Microglobulin in Detection of Early Nephropathy in African Diabetes Mellitus Patients
Table 2
Comparison of laboratory findings in both groups.
| | | Diabetics () | Controls () | |
| | Serum creatinine (μmol/L) | 91 (74–102) | 84 (69–98) | 0.03 | | Serum urea (mmol/L) | 4.6 (3.5–5.1) | 3.7 (2.6–4.9) | 0.003 | | Hemoglobin (g/dL) | 13.8 (13–14.8) | 14.2 (13.6–14.8) | 0.14 | | Serum uric acid (mmol/L) | 5.6 ± 1.5 | 5.0 ± 1.5 | 0.01 | | Random plasma glucose (mmol/L) | 12.0 ± 3.9 | 6.0 ± 1.6 | <0.001 | | Glycated hemoglobin (%) | 7.1 (5.3–8.1) | 4.6 (3.9–5.2) | <0.001 | | Total cholesterol (mg/dL) | 5.0 ± 1.4 | 3.5 ± 1.3 | <0.001 | | Triglycerides (mg/dL) | 2.13 ± 0.93 | 1.40 ± 0.81 | <0.001 | | LDL-cholesterol (mg/dL) | 3.0 (1.4–3.9) | 1.4 (1.02–1.7) | <0.001 | | HDL-cholesterol (mg/dL) | 1.1 (0.86–1.2) | 0.98 (0.86–1.2) | 0.83 | | Atherogenic ratio (total cholesterol/HDL) | 4.4 (3.2–6.9) | 3.3 (2.4–4.6) | <0.001 | | UAC (mg/L) | 23 (10–100) | 0.36 (0.3–10.2) | <0.001 | | Estimated (mL/min) | 68 (54–87) | 81 (58–104) | 0.02 | | Estimated (mL/min/1.73 m2) | 82.7 (67.1–97.9) | 88.7 (76.2–117.8) | 0.01 | | Estimated (mL/min/1.73 m2) | 82.5 (67.4–97.3) | 90.0 (75.7–109.8) | 0.004 | | Urinary β2m (μg/mL) | 0.41 (0.1–0.99) | 0.1 (0.1–0.41) | 0.002 |
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UAC: urinary albumin concentration; β2m: beta-2-microglobulin. Mean (SD). Median (IQR).
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