Research Article
Complex Monitoring of Biochemical and Radionuclide Parameters in Patients with Metastatic Renal Cell Carcinoma during Immunotherapy
Table 5
An effect of biochemical and radionuclide parameters on the prognosis for RF risk during immunotherapy.
| Before initiation of immunotherapy | A 1.2-fold increase in plasma creatinine level (±0.4) | A 1.6-fold increase in plasma urea level (±0.6) |
| Parameters of laboratory blood and urine tests () | Plasma creatinine level | | | Plasma urea level | | | Protein in urine | Trend = +0.3 () | = +0.5,
| Plasma TGF- | Trend = +0.3 () | Trend = +0.3 () | Plasma IL-17 | = +0.4,
| = +0.4,
|
| Parameters of complex renoscintigraphy with -technephore () | FSS, a total prognostic index for the urinary system | = +0.4,
| | Geff, an effective index of the renal concentration function | = −0.4,
| | , %, an excretion rate of -technephore from parenchyma | | = −0.5,
| Tev [min], the time of start of excretion of the labeled urine from the pyelocaliceal system | = +0.4,
| = +0.5,
| Tev [min], the time of start of excretion of the labeled urine from the renal pelvis | Trend = +0.3 () | = +0.5,
| Rnfsc, a visual sign of nephrosclerosis | = +0.4,
| |
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