Research Article

Complex Monitoring of Biochemical and Radionuclide Parameters in Patients with Metastatic Renal Cell Carcinoma during Immunotherapy

Table 5

An effect of biochemical and radionuclide parameters on the prognosis for RF risk during immunotherapy.

Before initiation of immunotherapyA 1.2-fold increase in plasma creatinine level (±0.4)A 1.6-fold increase in plasma urea level (±0.6)

Parameters of laboratory blood and urine tests  ()
Plasma creatinine level
Plasma urea level
Protein in urineTrend
= +0.3 ()
= +0.5, 
Plasma TGF-Trend
= +0.3 ()
Trend
= +0.3 ()
Plasma IL-17 = +0.4, 
= +0.4, 

Parameters of complex renoscintigraphy with  -technephore  ()
FSS, a total prognostic index for the urinary system = +0.4, 
Geff, an effective index of the renal concentration function = −0.4, 
, %, an excretion rate of -technephore from parenchyma = −0.5, 
Tev [min], the time of start of excretion of the labeled urine from the pyelocaliceal system = +0.4, 
= +0.5, 
Tev [min], the time of start of excretion of the labeled urine from the renal pelvisTrend
= +0.3 ()
= +0.5, 
Rnfsc, a visual sign of nephrosclerosis = +0.4,