Research Article

Renal Recovery following Liposomal Amphotericin B-Induced Nephrotoxicity

Table 3

Multivariable Cox model.

VariableHazard Ratio for At Least Partial Recovery (95 CI)p-value

Cumulative LAmB dose (per 5,000 mg)0.78 (0.52, 1.17)0.23
Concomitant nephrotoxins at AKI (per 1 nephrotoxin)0.81 (0.51, 1.27)0.35
Concomitant nephrotoxins after AKI (per 1 nephrotoxin)1.59 (0.88, 2.87)0.12
Age (per decade)1.03 (0.82, 1.29)0.82
Baseline eGFR (per 5 mL/min/1.73m2)1.00 (0.93, 1.09)0.91

LAmB prior to AKI+ LAmB after AKI (time dependent).
Glomerular filtration rate, calculated by CKD-EPI.