Health Facts Medication Adherence in Transplantation (H-MAT) Study: A Secondary Analysis of Determinants and Outcomes of Medication Nonadherence in Adult Kidney Transplant Recipients

Table 1

Condition, therapy, and health care team/system factors by post-transplant medication adherence and nonadherence.

	Overall n, % or mean, ±SD	Medication adherent n% or mean, ±SD	Medication non-adherent n, % or mean, ±SD	Medication non-adherent by category (non-adherence divided by overall)	value
Social/economic determinants
Gender
Male	8193 (49.16%)	7184 (48.96%)	1009 (50.58%)	12.32%	0.1765
Female	8474 (50.84%)	7488 (51.04%)	986 (49.42%)	11.64%
Age in years	53.21 ± 15.97	53.41 ± 16.00	51.7 3± 15.24		<0.0001
Race
African American	2936 (17.96%)	2585 (17.99%)	351 (17.80%)	11.95%	0.008
Asian/Pacific Islander	2261 (13.83%)	2017 (14.03%)	244 (12.37%)	10.79%
Caucasian	10992 (67.26%)	9623 (66.97%)	1369 (69.42%)	12.45%^a
Hispanic	153 (0.94%)	145 (1.01%)	8 (0.41%)	5.23%^a
Marital status
Divorced	897 (5.83%)	791 (5.85%)	106 (5.64%)	11.82%	<0.0001
Legally separated	160 (1.04%)	152 (1.13%)	8 (0.43%)	5.00%^a
Life partner	10 (0.06%)	8 (0.06%)	2 (0.11%)	20.00%
Married	8142 (52.90%)	7203 (53.32%)	939 (49.95%)	11.53%^b
Single	5189 (33.72%)	4460 (33.01%)	729 (38.78%)	14.05%^abc
Widowed	992 (6.45%)	896 (6.63%)	96 (5.11%)	9.68%^c
Condition-related determinant
Mental health or substance use diagnosis
No	15025 (90.13%)	13260 (90.5%)	1765 (88.47%)	11.75%	0.0082
Yes	1646 (9.87%)	1416 (9.65%)	230 (11.53%)	13.97%
Healthcare team/system-related determinants
Payer type
Commercial insurance	2502 (15.01%)	2286 (15.58%)	216 (10.83%)	8.63%^acde	<0.0001
Government	318 (1.91%)	272 (1.85%)	46 (2.31%)	14.47%^dg
HMO/managed care	2713 (16.27%)	2326 (14.85%)	387 (19.40%)	14.26%^cf
Medicaid	1321 (7.92%)	1178 (8.03%)	143 (7.17%)	10.82%
Medicare	6733 (40.39%)	5909 (40.26%)	824 (41.30%)	12.24%^ab
Self-pay/free (research)	649 (3.89%)	601 (4.10%)	48 (2.41%)	7.40%^bfgh
Others	2435 (14.61%)	2104 (14.34%)	331 (16.59%)	13.59%^eh