Review Article

Cystic Fibrosis: Brazilian ENT Experience

Table 1

Symptoms, polyps, tomography and mutations in Brazilian CF patients.

City: Sao Paulo City
Estate: Sao Paulo
Boari and Castro Júnior [24]
City: Botucatu
Sao Paulo
Weber and Ferrari [26]
City: Campinas
Sao Paulo
Sakano and colleagues [20]
City: Belo Horizonte
Minas Gerais
Franco and colleagues [22]
City: Porto Alegre Rio Grande do Sul
Franche and colleagues [25]

SymptomsCough (88.2%), headache or facial pain (38.2%)22% of them complained of oral breathingCough (45%), oral breathing (44%)34.8% reported nasal obstruction, ten (43,5%) complained of nasal secretion

Polyps 8.82%39.1%36%14%8.69

Tomography(i)Lund-Mackay average score of 13.3
(ii)considering criteria for the endoscopic diagnosis of chronic rhinosinusitis: 93.54%
According to Johansson and colleagues: grade I in four patients (44.4%), grade II in one patient (11.1%), and grade III in four patients (44.4%)Mucosal thickening in 50%, opacification of paranasal sinuses in 6% and pseudomucocele in 40%According to the Lund-Kennedy score: 14 children with nasal polyps had maximum scores

Mutation in ΔF508Out of 23 patients: 34% patients were found with the genetic mutation ΔF508/other, , , , , and 39% patients without specific mutationsOut of the 50 patients: heterozygotes, homozygotes, other mutations in 20%