Mucin Production and Mucous Cell Metaplasia in Otitis Media
Figure 9
Math1 plays an important role in the differentiation of mucous-like cells. (a) With Math1 being knocked down by antisense-Math1 (as-Math1), AB-PAS-positive cells are obviously reduced in cultured mouse middle ear epithelial cells. (b) With Math1 being upregulated by sense-Math1 (s-Math1), AB-PAS-positive cells are remarkably increased. RA, retinoid acid; TNFα, tumor necrotic factor alpha.
