Sinonasal Cancer and Occupational Exposure in a Population-Based Registry

Table 4

Occupational exposure to carcinogenic agents among subjects with sinonasal cancer, by smoking status^a; Lombardy region sinonasal cancer registry, 2008–2011 (𝑁=200 with interview).

Occupational exposure	Never smokers		Former smokers		Current smokers		𝑃 value^b
	No.	%	No.	%	No.	%
Never exposed	52	70.3	38	48.7	32	69.6	Reference
Ever exposed (any agent)	22	29.7	40	51.3	14	30.4	0.01
Wood dust	12	16.2	21	26.9	10	21.7	0.10
Leather dust	10	13.5	17	21.8	2	4.3	0.01
Nickel compounds	0	0.0	2	2.6	2	4.3	0.23
Chromium compounds	1	1.4	3	3.8	0	0.0	0.16
PAH	0	0.0	1	1.3	1	2.2	0.47
Cork dust	1	1.4	0	0.0	0	0.0	0.51

PAH: polycyclic aromatic hydrocarbons, SCC: squamous cell carcinoma.
^a10 subjects with missing smoking history were excluded.
^bFrom chi-square test (reference: never exposed).
Note: a subject may have been exposed to more than one agent in his/her occupational history.