Clinical Study

Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan

Table 4

Comparison of antimicrobial susceptibilities of MRSA and MSSA.

Antimicrobial agentResistance breakpoint ( 𝜇 g/mL)MSSA ( 𝑛 = 1 2 2 )MRSA ( 𝑛 = 1 4 )
Range (μg/mL)MIC90 (μg/mL)Resistance (%)Range (μg/mL)MIC90 (μg/mL)Resistance (%)

MPIPC4≦2≦204–>8>8100
ABPC0.5≦0.125–>161671.34–>16>16100
CCL161–1641.64–>16>1692.9
CDTR2*0.5 –210.82–>16>16100
CAM4≦0.125–>16>1667.2>16>16100
CLDM1≦0.125–0.250.250≦0.125–>16>1671.4
FOM8**0.25–>161620.51–>16814.3
MINO8≦0.125–0.25≦0.1250≦0.125–160.257.1
GM80.25–>16>1654.11–>16>1692.9
VCM4≦0.5–1101-210
NDFX4**≦0.125–2≦0.1250≦0.125–>16≦0.1257.1
FA2**≦0.125–>160.50.82≦0.125–10.50

The breakpoints for these antimicrobial agents were determined according to the interpretation criteria of Clinical and Laboratory Standards Institute (CLSI). Susceptibility to antimicrobial drugs for which breakpoints are not determined by CLSI was according to the interpretation criteria of the Japan Society for Chemotherapy (*) or defined in this study (**).