Table 2: Factors associated with plasma chloride (mmol/L), SID, and tCO2 levels (mmol/L) at multivariate analysis in 107 infants <33 weeks of GA.

𝑃 valueIncremental 𝑟 2 Beta coefficient

Plasma chloride*
Chloride intake<0.0010.14+
HsPDA<0.010.03+
Sodium intake<0.010.02
Weight loss % of BW<0.010.02+
GA<0.050.01

SID**
Chloride intake<0.0010.09
HsPDA<0.010.04
Sodium intake<0.050.01+
Phosphate intake<0.050.01+
GA<0.050.01+

tCO2***
Chloride intake<0.0010.13
GA<0.010.02+
Sodium intake<0.050.01+

(SID) strong ion difference; (tCO2) total carbon dioxide; (hsPDA) hemodynamically significant patent ductus arteriosus; (BW) Birth weight; (GA) gestational age;
*General 𝑟 2 = 0 . 2 2 ; **General 𝑟 2 = 0 . 1 6   ***General 𝑟 2 = 0 . 1 6 .