Features and Outcomes In Utero and after Birth of Fetuses with Myocardial Disease

Table 1

Data of cases with DCM and myocarditis.

Type of CMP	N.	W.g. at dg.	Assoc. ECAs	Hydrops	Arrh.	Ther. in utero	Outcome in utero-w.g.; TP IUD Delivery	Postnatal death	Total death of cases continuing pregn.	Alive/age
DCM LV; Idiopathic	Tot. 18; 13; (1 Fam.,; 3 NCM,; 5 EFE)	18–35, (median 26)		9	1-SVT; 1 ExS	3-dig. 3–4 d	1 TP; 2 IUD (24, 30 w.g.); 2 lost, 8 delivered at 33–36 w.g.	4 died		5 alive at 3–10 yrs, improved after 3 months–1 yr
With ECA	5 (3 EFE)		2 renal,; 1 CNS,; 1 thor.cyst,; 1 multiple; malform.	3			5 delivered at 34–36 w.g.	4 died
DCM RV	1	32		1		Dig.; 14 d	Delivered by CS at 34 w.g.	Died; at day 1
DCM total	19	18–34	5 ECAs	13 (68.4%)	1 SVT	4 dig.	1 TP,; 2 IUD, 2 lost	9 died (4 ECAs)	11/16; (2 lost) =68.75%	5/16 alive (31.25%) and improved
Myocarditis	12	20–37; (median 23)		11 (91.7%); (5 severe, 5 moder., 1 mild)			1 TP,; 4 IUD at 23–30 w.g.; 7 delivered at 28–40 w.g., median 33	3 died; at day 1	7/11 = 63.6%	4 alive, improved

DCM LV, DCM RV: dilated cardiomyopathy of the left ventricle/right ventricle, n.: number, w.g.: weeks’ gestation, dg.: diagnosis, Fam.: familiarity, NCM: noncompacted myocardium, ECAs: extracardiac anomalies, malform.: malformations, CNS: central nervous system, thor.: thoracic, arrh.: arrhythmias, SVT: supraventricular tachycardia, ExS: supraventricular extrasystolia, ther.: therapy, dig.: digoxin, d: day, yr: years, TP: termination of pregnancy, IUD: intrauterine death, HF: hydrops fetalis, moder.: moderate, CS: caesarean section, and f-up: follow-up.