Induced Sputum Substance P in Children with Difficult-to-Treat Bronchial Asthma and Gastroesophageal Reflux: Effect of Esomeprazole Therapy

Table 3

Correlations between studied parameters in asthmatic patients with reflux in children with difficult-to-treat asthma.

Correlation between	r	P
Reflux severity score and C-ACT	−0.74	<0.001*
Reflux severity score and FEV1	−0.64	<0.001*
Reflux severity score and PEFV	0.65	<0.001*
Reflux severity score and induced sputum SP	0.80	<0.001*
Induced sputum SP and ACT	−0.67	<0.001*
Induced sputum SP and FEV1	−0.49	<0.001*
Induced sputum SP and PEFV	0.45	<0.001*

C-ACT: childhood asthma control test; EFV₁: forced expiratory volume in 1 second; PEF variability: peak expiratory flow variability; sputum SP: sputum levels of substance P.
*Significant.