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| Gene | Gene symbol | Relevant biological function |
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| Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | ACE | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. |
| Cholecystokinin A receptor | CCKAR | In the central and peripheral nervous system this receptor regulates satiety. |
| Cannabinoid receptor 1 (brain) | CNR1 | Animal experiments utilizing receptor antagonists resulted in suppressed food and water intake with concurrent decreased body weight. |
| Corticotropin releasing-hormone | CRH | Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. |
| Corticotropin releasing-hormone receptor 1 | CRHR1 | The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including obesity. |
| Diencephalon/mesencephalon homeobox 1 | DMBX1 | This gene is known to be involved in adult feeding behavior and may play a role in brain and sensory organ development. |
| Free fatty acid receptor 1 | FFAR1 | The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. |
| Glutamate decarboxylase 2 (pancreatic islets and brain, 65 kDa) | GAD2 | This gene has been shown to be a candidate gene for obesity in humans. |
| Galanin-like peptide | GALP | This gene is involved in biological processes including hypothalamic regulation of metabolism. |
| Galanin receptor 3 | GALR3 | The neuropeptide galanin modulates a variety of physiologic processes including feeding behavior. |
| Glucagon | GCG | Glucagon is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. |
| Growth hormone secretagogue receptor | GHSR | The encoded protein may play a role in energy homeostasis and regulation of body weight. |
| Glucagon-like peptide 1 receptor | GLP1R | This gene is involved in energy reserve metabolic processes and feeding behavior. |
| Glutamate receptor, ionotropic, N-methyl D-aspartate 2B | GRIN2B | NMDA receptor channel is involved in the activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. |
| Hypocretin (orexin) receptor 2 | HCRTR2 | The protein encoded by this gene is a G protein coupled receptor involved in the regulation of feeding behavior. |
| Histamine receptor H3 | HRH3 | This gene encodes an integral membrane protein and can regulate neurotransmitter release. |
| 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled | HTR1A | Gene has been shown to be involved in control of food intake in obese rats. |
| 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled | HTR2C | This gene is involved in feeding behavior. |
| Interleukin 1 receptor antagonist | IL1RN | The protein encoded by this gene is a member of the interleukin 1 cytokine family. |
| Janus kinase 1 | JAK1 | Knockout mice of this gene exhibit decreased nursing behavior. |
| Junctophilin 1 | JPH1 | This gene is involved in muscle organ development. |
| Lactalbumin, alpha | LALBA | This gene encodes alpha-lactalbumin, a principal protein of milk. |
| Leptin receptor | LEPR | This protein is a receptor for leptin and is involved in the regulation of fat metabolism. |
| Melanin-concentrating hormone receptor 1 | MCHR1 | The gene is involved in the neuronal regulation of food consumption. |
| NK2 homeobox 1 | NKX2-1 | This gene is involved in brain development and feeding behavior. |
| Neuropeptide Y receptor Y1 | NPY1R | Neuropeptide Y exhibits a diverse range of important physiologic activities including regulation of food consumption. |
| Neuropeptide Y receptor Y2 | NPY2R | This gene is involved in regulating feeding behavior. |
| Neurotrophic tyrosine kinase, receptor, type 2 | NTRK2 | This gene is involved in feeding behavior. Mutations in this gene have been associated with obesity. |
| Opioid receptor, kappa 1 | OPRK1 | This gene is involved in regulating behavior. |
| Peroxisomal biogenesis factor 13 | PEX13 | This gene is involved in suckling behavior. |
| POU class 4 homeobox 1 | POU4F1 | This gene is highly expressed in the developing sensory nervous system. |
| Prolactin releasing hormone | PRLH | This gene is involved in feeding behavior and regulates multicellular organism growth. |
| Prostaglandin E receptor 3 (subtype EP3) | PTGER3 | This receptor may have many biological functions, which involve digestion and the nervous system. |
| PTK2 protein tyrosine kinase 2 | PTK2 | This gene plays a role in glucose response, fat-cell differentiation, and the growth hormone receptor signaling pathway. |
| Peptide YY | PYY | This gene is involved in digestion and feeding behavior. |
| Solute carrier family 18 (vesicular monoamine), member 2 | SLC18A2 | This gene is involved in glucose homeostasis and response to starvation. |
| Solute carrier family 27 (fatty acid transporter), member 5 | SLC27A5 | This gene is involved in digestion. |
| Tachykinin receptor 1 | TACR1 | This gene is involved in eating behavior. |
| Tyrosine hydroxylase | TH | This gene plays a role in eating behavior. |
| Thyrotropin-releasing hormone | TRH | This gene plays a role in eating behavior. |
| Transient receptor potential cation channel, subfamily M, member 5 | TRPM5 | This gene plays an important role in taste transduction. |
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