Review Article

Kidney Disease and Youth Onset Type 2 Diabetes: Considerations for the General Practitioner

Table 2

Recommended treatment targets that may reduce risk of nephropathy in youth with type 2 diabetes.

Clinical parameterInterventionTreatment target

Glycemic controlLifestyle/Insulin/MetforminHbA1c ≤ 7%
Prehypertension [44] (bp > 90th–95th)LifestyleBp < 90th percentile
Hypertension [44] (bp > 95th percentile)Lifestyle ± Ace inhibitor or Angiotensin II Receptor BlockerBp < 90th percentile
Dyslipidemia LDL ≥2.6 mmol/LLifestyleLDL < 2.6 mmol/L
Dyslipidemia LDL >4.1 mmol/LLifestyle + StatinLDL < 2.6 mmol/L
Overweight and ObesityLifestyleBMI < 85th percentile
SmokingCessation strategies Nonsmoker