Table 4: Relationship among asthma morbidity, mold sensitivity and airborne mold, endotoxin, or glucan concentrations.

OutcomeaConcentrationbSensitivitycAllergen
Indoor moldP Outdoor moldP EndotoxinP β-GlucanP

N Above medianPositive44493526
Negative46413328
Below medianPositive49443933
Negative41463222

Maximum symptom daysAbove medianPositive5.396.207.146.38
Negative5.12<0.016.630.547.210.756.500.96
Below medianPositive8.107.507.627.00
Negative7.856.206.316.45

Daytime symptomsAbove medianPositive4.025.226.115.92
Negative4.07<0.015.320.915.550.974.930.89
Below medianPositive6.825.806.035.52
Negative6.515.135.915.41

Night symptomsAbove medianPositive3.053.513.634.15
Negative2.150.062.980.332.820.502.750.43
Below medianPositive4.474.114.383.42
Negative3.442.573.382.36

Slow playAbove medianPositive2.823.043.372.77
Negative1.980.032.540.233.300.172.610.97
Below medianPositive4.244.163.922.91
Negative3.542.871.943.05

Caretaker changed
plans
Above medianPositive0.701.001.201.23
Negative0.410.050.800.900.670.440.500.42
Below medianPositive1.221.000.720.79
Negative1.220.781.130.95

aUnits are “number of days in the past 2 weeks.” P values test for an interaction between allergen sensitivity and concentration for the given outcome.
bMedian concentrations: indoor mold—514 spores/m3, outdoor mold—3840 spores/m3, endotoxin—12 EU/mg, β-Glucan—0.4 μg/g.
cFour or more skin test wheals that are at least 3 mm greater than the negative control out of 14 mold skin tests measured.