Clinic-Based Retrospective Analysis of Psychopharmacology for Behavior in Fragile X Syndrome

Figure 3

Reason for failure of various classes of medications during treatment trials. Green areas of charts indicate percent of individuals for whom no follow-up information was available, Red areas indicate failure due to medication ineffectiveness, and Blue sections of charts represent individuals failing due to a side effect that limited treatment. For antidepressants and antipsychotics data is presented separately for children and adolescents less than 18 and adults 18 and over to compare rates of intolerable side effects in these age groups. For alpha2-agonists and stimulants, only 1 and 5 individuals, respectively, aged 18 or over failed treatment, all due to medication ineffectiveness. Therefore, age groups were not presented separately for these medication classes.