Clinical Study
Doxapram Use for Apnoea of Prematurity in Neonatal Intensive Care
Table 3
Short-term outcome of the patients who received doxapram.
| | Total | Successfully treated patients () | Unsuccessfully treated patients () | | | (%) | Median (IQR) (min–max) | % | Median (IQR) | % | Median (IQR) |
| Neonatal survival# | 117/122 (95.9) | | 1/79 (98.7) | | 4/37 (89.2) | | 0.035 | Number of ventilatory days | | 7 (12) (0–72) | | 5 (12) | | 11 (13) | <0.001 | Number of NICU days | | 38 (31) (6–120) | | 33 (26) | | 42 (34) | 0.002 | Pneumothorax | 6/122 (4.9) | | 3/76 (3.9) | | 2/37 (5.4) | | 0.65 | Corticosteroids for detubation | 27/122 (22.1) | | 11/79 (13.9) | | 13/37 (35.1) | | 0.013 | NEC | 27/122 (22.1) | | 15/79 (19.0) | | 10/37 (27.0) | | 0.34 | IVH (all grades) | 40/122 (32.8) | | 23/79 (29.1) | | 16/37 (43.2) | | 0.15 | PVL (all grades) | 35/120 (29.2) | | 19/78 (24.4) | | 14/36 (38.9) | | 0.13 | Persistent ductus arteriosus | 44/122 (36.1) | | 26/79 (32.9) | | 14/37 (37.8) | | 0.68 | ROP | 17/112 (15.2) | | 8/72 (11.1) | | 7/34 (20.6) | | 0.24 |
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Mann-Whitney test and Fisher’s Exact test.
#No patients died during doxapram treatment.
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