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International Journal of Pediatrics
Volume 2013 (2013), Article ID 690432, 7 pages
http://dx.doi.org/10.1155/2013/690432
Research Article

Adaptive Behavior in Young Children with Neurofibromatosis Type 1

1University of Wisconsin - Milwaukee, Milwaukee, WI 53201, USA
2Medical College of Wisconsin, Milwaukee, WI 53226, USA

Received 29 April 2013; Revised 26 September 2013; Accepted 30 September 2013

Academic Editor: Joel R. Rosh

Copyright © 2013 Bonita P. Klein-Tasman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Neurofibromatosis-1 is the most common single gene disorder affecting 1 in 3000. In children, it is associated not only with physical features but also with attention and learning problems. Research has identified a downward shift in intellectual functioning as well, but to date, there are no published studies about the everyday adaptive behavior of children with NF1. In this study, parental reports of adaptive behavior of 61 children with NF1 ages 3 through 8 were compared to an unaffected contrast group ( ) that comprised siblings and community members. Significant group differences in adaptive skills were evident and were largely related to group differences in intellectual functioning. In a subsample of children with average-range intellectual functioning, group differences in parent-reported motor skills were apparent even after controlling statistically for group differences in intellectual functioning. The implications of the findings for the care of children with NF1 are discussed.