Review Article

Flow Cytometry in the Detection of Neonatal Sepsis

Table 2

Cell surface markers, chemokines, cytokines, and adhesion molecules were found to play a role in neonatal sepsis pathogenesis; *might even be relevant in diagnostic use, and thus, is described in the text.

Cell surface markers

NeutrophilsCD11b* , CD64* [22, 37, 39]
LymphocytesCD3, CD19, CD25, CD45RA, CD45RO, CD62, CD69[6, 3941]
MonocytesHLA-DR* [5, 39, 42]

Chemokines, cytokines, adhesion molecules

IL-1β, IL-1ra, IL-2, sIL-2R, IL-4, IL-5, IL-6*, IL-8, IL-10, TNF-α, 11sTNFR-p55, 12sTNFR-p75, IFNc[4349]
E-selectin, L-selectin
Soluble intracellular adhesion moleucule-1 (sICAM-1)
Vascular cell adhesion molecule-1 (VCAM-1)