Neonatal Thrombocytopenia after Perinatal Asphyxia Treated with Hypothermia: A Retrospective Case Control Study

Table 3

Morbidity, clinical findings, and presence of hemorrhage on neuroimaging.

	Hypothermia	Control	value	OR [95% CI]
	group	group
Seizures— (%)	45 (83%)	34 (74%)	.25	1.77 [0.67–4.67]
Treatment with >2 types of anticonvulsants— (%)	18 (33%)	8 (18%)	.07	2.38 [0.92–6.14]
Neonatal sepsis	3 (6%)	2 (4%)	.78	1.29 [0.20–8.10]
SGA	0 (0%)	2 (4%)	.12	∞
IVH grades II-III on cranial US— (%)	1 (2%)	1 (2%)	.92	0.87 [0.05–14.24]
Cerebral bleeding on MRI— (%)	11 (23%)	8 (23%)	.95	1.03 [0.37–2.91]
Mild	8 (17%)	5 (14%)	.64
Moderate/severe	3 (6%)	3 (9%)	.64
Type of moderate/severe hemorrhage
Subdural	0 (0%)	0 (0%)	—
Intraparenchymal	2 (4%)	2 (6%)	.74
Intraventricular	2 (4%)	1 (3%)	.76
Mortality— (%)	17 (31%)	9 (20%)	.18	1.89 [0.75–4.78]
Mechanical ventilation days*	4.8 (2.94)	3.6 (3.40)	.07	1.13 [0.99–1.28]
Hospital days*	10.7 (7.07)	10.4 (8.46)	.89	1.00 [0.95–1.06]

SGA: small for gestational age; IVH: intraventricular haemorrhage; US: ultrasound; MRI: magnetic resonance imaging; ∞: infinite (because of zero value in one group); *value given as mean (SD).