Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication

Figure 4

Selected scenarios in the mixed-effects model adjusted for sex, age at diagnosis, risk profile, and corticosteroid exposure. Predicted means for BMI -scores and 95% confidence intervals for (a) 2 y at diagnosis with standard risk, (b) 4 y at diagnosis with standard risk, (c) 6 y at diagnosis with standard risk, (d) 8 y at diagnosis with standard risk, (e) 10 y at diagnosis with high risk, and (f) 12 y at diagnosis with high risk. Dotted lines are means of healthy (Raine study) individuals. The horizontal axes are age in years, starting from the age at diagnosis for each scenario.

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