537639.fig.001a
537639.fig.001b
Figure 1: Mapping of MIF-1-induced brain activation of c-Fos immunoreactivity and icv and iv administration. Vertical panel (a) represents the control brain, panel (b) represents c-Fos immunoreactivity 4 hours after icv injection of MIF-1 (1  𝜇 g/mouse), and panel (c) represents c-Fos immunoreactivity 4 hours after iv injection of MIF-1 (10  𝜇 g/mouse). Horizontal rows 1–7 represent various sections of the brain from the anterior to the posterior part of the brain. The distances from interaural and bregma in mm are 1: 5.58 and 1.78, 2: 4.54 and 0.74, 3: 4.06 and 0.26, 4: 3.46 and − 0 . 3 4 , 5: 5.58 and 1.78, 6: 2.34 and − 1 . 4 6 , 7: 1.10 and − 2 . 7 0 .