An Overview of Brain-Derived Neurotrophic Factor and Implications for Excitotoxic Vulnerability in the Hippocampus
Figure 2
Neurotrophin signal involvement in targeting of growing neurons. (a) Both TrkA and p75NTR are activated on the growing neuron, survival and growth continues; (b) on the growing neuron, p75NTR is activated by BDNF, but no TrkA activation takes place, so apoptosis occurs. Adapted from [67].