An Overview of Brain-Derived Neurotrophic Factor and Implications for Excitotoxic Vulnerability in the Hippocampus

<table>BDNF involvement in the development of hyperexcitable circuits in the hippocampus; although this cycle serves to support LTP and plasticity, it can become overwhelmed under certain excitotoxic conditions and serve to further promote those conditions.</table>

International Journal of Peptides

fig4

Figure 4

Figure 4: An Overview of Brain-Derived Neurotrophic Factor and Implications for Excitotoxic Vulnerability in the Hippocampus 