Research Article

Large Scale Solid Phase Synthesis of Peptide Drugs: Use of Commercial Anion Exchange Resin as Quenching Agent for Removal of Iodine during Disulphide Bond Formation

Figure 4

HPLC Chromatograph of desmopressin with incomplete removal of iodine In such cases, the peptide dissolved in water added the resin and stirred for 5 min’s filtered and Lyophilized. The HPLC analysis (Figure 5) showed not even traces of iodine present.
323907.fig.004