Significant Increase in Salivary Substance P Level after a Single Oral Dose of Cevimeline in Humans

<table>Effects of a single oral dose of cevimeline (•) or placebo (°) on plasma levels of substance P (SP) (a), calcitonin gene-related peptide (CGRP) (b), and vasoactive intestinal polypeptide (VIP) immunoreactive substance (c). Values are means ± SD, <svg height="10.925" id="M28" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 10.925" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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International Journal of Peptides

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Figure 4

Figure 4: Significant Increase in Salivary Substance P Level after a Single Oral Dose of Cevimeline in Humans 